Professor Brian J. Druker, M.D.
2018 in Medicine
Professor Brian J. Druker, M.D. made a significant research discovery in the field of targeted cancer therapy. He developed a prototype drug called “Imatinib” for treatment of chronic myeloid leukemia (CML).
Imatinib inhibits BCR-ABL, a specific protein that is only detected in cells of CML patients, not in a normal cell. This specificity can thus minimise a side effect during treatment. From a laboratory research, the drug has been tested on animals and humans and has been found to reduce severity, mortality and morbidity from CML. Without imatinib, CML patients usually deteriorate and die within 3 years. Currently, other drugs for targeted therapy have been developed for treatment of other cancers
ProfessorBrian J. Druker, M.D.
Oregon Health& Science University
3181 SW Sam Jackson Park Road
Portland, Oregon 97239